Identification of HBV genotype-specific tag sequences / 中华肝脏病杂志

<p><b>OBJECTIVE</b>To identify the HBV genotype-specific tag sequence.</p><p><b>METHODS</b>The large S region sequences from 930 HBV genomes were aligned to identify the genotype-specific tag sequences. PCR was used to check the genotyping effect of these tags.</p><p><b>RESULTS</b>Two tag sequences, sequence between 149-169 and sequence between 461-483, were identified in the large S region. Using primers specific to these tag sequences, the genotype of HBV can be specifically identified.</p><p><b>CONCLUSION</b>These tag sequences can be used for HBV genotyping.</p>